Monday, 23 October 2017

A Closer look at TAC

Based on information in the previous writings let us take just one item and look at it more closely.....

So in Tay Sachs one codon that reads incorrectly is TAC which should match up to ATG but instead it is matched with TAG ...... one observation is that TAG is an indicator to STOP end of the journey.... yet instead it should match to ATG which is MET or Start point..... a leader and not an end point. Both the codons ATG and TAG contain red, yellow and green colours like a set of traffic lights if it starts with A it gives them the green light if it starts with T is gives them the red light of Stop. What else might have happened if this stop light had been on green for go...  

Stop codons TAA Ochre... TAG Amber...TGA Opal...... all start with a STOP red light two have A at the centre which is GO only TGA has the order correct Red, Amber, Green......is TAG unsure about whether to stop or not......more like STOP, GO and hang on a minute.

Observation ..TAC is Hydrophobic and has the option to become Neutral on the rung of a ladder.... TAG is Hydrophilic and Neutral and ATG is Hydrophobic and cannot be Neutral. So although TAC is probably Hydrophobic with TAG it would have to become Neutral or Hydrophilic with ATG.

Observation ...in the musical notes of TAC and TAG we see that TAC raises the tone by 1/2 a note and when it is with its true match ATG it is also raising the tone by 1/2 a note so no change there but the difference musically between TAG and ATG is zero. That said TAC plays in C Major.... TAG plays in B Major and ATG also plays in B Major hence there is no change.

Observation ... TAC and TAG have two letter errors T should become A and A should have become T instead they did not change at all.......C and G did change as would be expected.

So much to observe and so much fun in doing so. Enjoy your thinking x


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