Tuesday, 15 May 2012

Map 260 Duchenne Muscular Dystrophy


Duchenne Muscular Dystrophy

I thought I would spend some time thinking about the repeats of DNA that cause problems for people with Duchenne Muscular Dystrophy. They have repeats of CAG and GCG.

It rang a bell and upon checking the article on Huntington's Disease I found that repeats of CAG cause the problems with MD.

Having said that errors when coding for RNA with CAG also have the potential to produce the error GCG. This leads me to wonder if repeats of the same letters are more likely for a variety of illnesses. If you are interested in D.M.D. It might be worth reading the article on Huntington's.

Thinking further it stands to reason that Proline which is so supportive of weakened muscles and joints must have a part to play in the world of Duchennes and as proline is made from the codons CCC, CCT, CCA and CCG these four are associated with the body parts of chest and reproductive organs strongly,  and to a lesser degree feet, liver, skeleton and circulation. 

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