As can be seen on the DNA and RNA maps or on the amino acid maps some amino acids are hydrophobic and some are hydrophilic in some cases when a pair don't match up one of them might need to become neautral so it can adapt to the situation it finds itself in.
The sugar phosphate backbone of DNA is hydrophlic and likes to be close to water. The interior part of the DNA is hydrophobic and likes to stay dry on the inside.
Various maps are marked * for hydrophobic N for Neutral or have no marks for hydrophilic.
All hexagrams manage to match up in pairs of hydrophobic and hydrophilic if they don't then one of them can become neutral and change according to requirements.
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